Pakistan’s First Sublingual Mecobalamin with D3 and K2
₨ 1,200
Composition:
Each Tablet Contains:
Mecobalamin (USP) …………………………………….. 1000 mcg
Vitamin K2 (Mk7) (USP) ……………………………… 90 mcg
Vitamin D3 (Cholecalciferol) ………………………… 5000 IU
Vitamin B6 (USP) ……………………………………….. 1.5 mg
Top Benefits of Mecobalamin
Enhanced Neurological Function & Nerve Repair - Mecobalamin (B12) promotes myelin sheath formation and nerve regeneration, crucial for treating neuropathy and cognitive decline .
- Vitamin B6 supports neurotransmitter synthesis (e.g., serotonin, dopamine), improving brain signaling and reducing cognitive fatigue .
- Sublingual delivery ensures rapid absorption, bypassing gut limitations for immediate neurological support .
Cardiovascular Protection via Homocysteine Regulation
- B6 + Mecobalamin co-activate enzymes that convert homocysteine to methionine, lowering elevated homocysteine levels—a key risk factor for atherosclerosis and stroke .
- Vitamin K2 (MK-7) prevents arterial calcification by activating matrix Gla protein (MGP), reducing arterial stiffness .
Optimized Bone Mineralization & Calcium Utilization
- Vitamin D3 enhances intestinal calcium absorption . - Vitamin K2 (MK-7) directs calcium to bones by activating osteocalcin, improving bone density and reducing fracture risk by 30%
- Synergy prevents vascular calcification while supporting skeletal health .
Mitochondrial Energy Production & Reduced Fatigue
- Mecobalamin and B6 are cofactors in cellular energy metabolism:
- B12 enables folate-dependent DNA synthesis for red blood cell production .
- B6 facilitates glycogen breakdown and ATP generation .
- Sublingual B12 ensures bioavailability for rapid energy boost, critical in deficiency states .
Inflammation Reduction & Immune Modulation
– Vitamin D3 regulates immune cell function (e.g., T-cells, macrophages), lowering pro-inflammatory cytokines linked to autoimmune diseases .
– Vitamin K2 suppresses NF-κB signaling, reducing inflammatory markers like IL-6 .
– Clinical trials show D3/K2 combination alleviates Long COVID symptoms (e.g., fatigue, pain) .
Hormonal Balance & Mood Stabilization
– Vitamin B6 is essential for synthesizing GABA and serotonin, reducing anxiety and depression risk by 30% in observational studies .
-Vitamin D3 upregulates tryptophan hydroxylase, enhancing serotonin production .
Telomere Protection & Anti-Aging Effects
– Vitamin D3 supplementation slows telomere shortening in leukocytes, equivalent to delaying biological aging by 3 years per the VITAL trial .
– Mechanism involves D3-mediated reduction in oxidative stress and DNA damage .
Prenatal Health Support
– Vitamin B6 (at doses ≥10mg) reduces pregnancy-related nausea by modulating neurotransmitter activity.
– Vitamin D3/K2 ensures fetal skeletal development and prevents maternal bone loss .
Antioxidant Defense & Cellular Detoxification
– Mecobalamin regenerates glutathione, the body’s master antioxidant .
– Vitamin B6 supports heme synthesis, reducing oxidative stress in erythrocytes.
Gut-Brain Axis Optimization
– Vitamin K2 maintains gut barrier integrity, reducing endotoxin translocation linked to neuroinflammation .
– B Vitamins modulate gut microbiome diversity, influencing neurotransmitter production.
Key Mechanisms & Synergies
| Nutrient | Primary Role | Synergistic Partner | Enhanced Benefit | Vitamin K2 | Activates osteocalcin & MGP | D3 | Prevents Soft-Tissue Calcification | Vitamin D3 | Boosts Calcium Absorption | K2 | Directs Calcium to Bones/Teeth | | Mecobalamin | Supports Nerve Myelination | B6 | Improves Neurotransmitter Synthesis |
Dosage Considerations & Safety
- Vitamin D3 (5000 IU): Effective for deficiency correction; aligns with Endocrine Society guidelines for adults .
- Vitamin K2 (90 mcg MK-7): Optimal for activating K-dependent proteins without interacting with anticoagulants .
- Mecobalamin (1000 mcg): High dose suitable for neuropathy; excess excreted renally .
- Vitamin B6 (1.5 mg): Below the upper limit (100 mg/day); avoids sensory neuropathy risk .
Note: Sublingual delivery enhances bioavailability for B12 and B6, critical for patients with malabsorption or gut issues . Consult a healthcare provider before use if on warfarin (due to K2) or high-dose B6 supplements.
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